منابع مشابه
The Effect of Diphenylhydantoin
This work was previously published in abstract form in Clin. Res. 17: 288, 1969. Dr. Larsen's present address is the Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213. Received for publication 10 November 1969 and in revised form 4 February 1970. concentration. If free thyroxine is the only portion of the hormone available for cellular utilization, then ...
متن کاملElectrophysiologic properties of diphenylhydantoin.
The electrophysiologic properties of diphenylhydantoin (DPH) (5-10 mg/kg) intravenously was studied in 14 subjects using His bundle recordings and correlated with blood levels. Conduction through the A-V conducting system (AVCS) was studied at various paced atrial rates and refractory periods determined using programmed atrial premature depolarization within 10 min of drug administration. In 11...
متن کاملThe effect of diphenylhydantoin on insulin response.
1. Serum immunoreactive insulin, glucose tolerance and growth hormone levels were estimated in healthy volunteers before and after receiving diphenylhydantoin sodium (DPH) for 14 days. 2. With a standard oral dose of DPH all subjects showed a reduced insulin response to oral glucose (1 1 4 % ) . This correlated with the serum concentration of the drug, which ranged from 30.5 to 90.0 pmol/l (7.7...
متن کاملAngioimmunoblastic lymphadenopathy in a patient taking diphenylhydantoin.
The premise that chronic antigenic stimulation may be involved in lymphoproliferative disorders was considered in a patient with angioimmunoblastic lymphadenopathy who had received diphenylhydantoin (DPH) for seizure. This patient had clinical features overlapping with systemic lupus erythematosus (SLE) and serum antibody directed against DPH. It was proposed that the syndrome was caused by chr...
متن کاملSEIZURE DUE TO DIPHENYLHYDANTOIN -METHYLPHENIOATE INTERACTION
Signs and symptoms of D PH toxicity were seen in an epileptic child who had received DPH and MP concurrently. In the absence of liver and kidney disease and any intercurrent infection, and with the patient's recovery following the withdrawal of DPH, it appears that drug-drug interaction is the most logical explanation for DPH intoxication.
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ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 1974
ISSN: 0009-9236
DOI: 10.1002/cpt1974164727